WebSep 27, 2024 · Abstract. Replication-associated single-ended DNA double-strand breaks (seDSBs) are repaired predominantly through RAD51-mediated homologous recombination (HR). Removal of the non-homologous end-joining (NHEJ) factor Ku from resected seDSB ends is crucial for HR. The coordinated actions of MRE11-CtIP nuclease activities … WebMarc Audebert‡, Bernard Salles§, and Patrick Calsou From the Institut de Pharmacologie et de Biologie Structurale, CNRS UMR 5089, 205 route de Narbonne, F-31077 Toulouse Cedex, France The efficient repair of DNA double-strand breaks (DSBs) is critical for the maintenance of genomic integ-rity. In mammalian cells, the nonhomologous end-join-
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WebSep 25, 2024 · The nickel (II) complex of guanidinium phenyl porphyrin, a specific G-quadruplex ligand, targets telomeres and leads to POT1 mislocalization in culture cells. … WebThe efficient repair of DNA double-strand breaks (DSBs) is critical for the maintenance of genomic integrity. In mammalian cells, the nonhomologous end-joining process that represents the predominant repair pathway relies on the DNA-dependent protein kinase (DNA-PK) and the XRCC4-DNA ligase IV complex. Nonetheless, several in vitro and in … fan and cold
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WebDr. Carolyn Y. Muller is a Obstetrician-Gynecologist in Albuquerque, NM. Find Dr. Muller's phone number, address, insurance information, hospital affiliations and more. WebSelect where to authenticate from the dropdown, then click the Login button. WebMay 10, 2024 · Figure 2—source data 3: Source data related to Figure 2F. The tiff files correspond to uncropped pictures of the AlexaFluor647 fluorescence signal, acquired on an Odyssey LI-COR, of a scan of the membrane stained with Ponceau S, for the upper part (supernatant), and of the chemiluminescent signal acquired using autoradiographic films … cordless spotlight review