Tug1 lncrna
WebJan 29, 2024 · LncRNA TUG1 reduces inflammation and enhances insulin sensitivity in white adipose tissue by regulating miR-204/SIRT1 axis in obesity mice. LncRNA TUG1 competitively binds to miR-340 to accelerate myocardial ischemia-reperfusion injury. The Tug1 lncRNA locus is essential for male fertility. WebLncRNA TUG1 has also been shown to disrupt the expression of the Homeobox (HOX) gene family, such as HOXB7, thereby leading to an aging phenotype . LncRNA TUG1 is highly expressed in the human subependymal zone of the brain and is involved in age-related neurodegenerative diseases such as ischemic stroke and Huntington’s disease …
Tug1 lncrna
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WebTUG1 (taurine upregulated gene 1) is a long non-coding RNA expressed in the retina and in the brain. It was first identified in a screen for genes upregulated by in developing retinal … WebThe lncRNA TUG1, short for Taurine upregulated gene 1, was originally reported to be upregulated in response to taurine treatment of developing mouse retinal cells and has been frequently described as an oncogene in various human cancers. 34–36 UCA1 (urothelial carcinoma associated 1) was initially identified in human bladder carcinoma and ...
WebNov 6, 2024 · Taurine upregulated gene 1 ( TUG1) is a long noncoding RNA (lncRNA) that is downregulated in sepsis. The current study was designed to explore the role of EPCs … WebAug 2, 2016 · Long noncoding RNAs (lncRNAs) play crucial roles in tumorigenesis, and lncRNA taurine-upregulated gene 1 (TUG1) has been proven to be associated with several human cancers. However, the mechanisms of TUG1-involved regulation remain largely unknown. We examined the expressions of TUG1 in a cohort of 89 patients with non …
WebAug 2, 2016 · The lncRNA taurine-upregulated gene 1 ( TUG1) is a nonprotein-coding gene located on chromosome 22q12.2 that transcribes to a 6.7-kilobase-long, spliced, and … WebTUG1 lncRNA is involved in various aspects of tumor progression, including cell proliferation, migration, and invasion. Downregulation of TUG1 by therapeutic agents …
WebAug 8, 2024 · Next, we identified that lncRNA taurine upregulated gene 1 (TUG1)acted as a competing endogenous RNA for microRNA-222–3p (miR-222–3p)and subsequently …
WebMar 28, 2024 · LncRNA TUG1 promotes neuronal apoptosis through inhibition of mitophagy. TUG1 decreased SIRT1 expression by promoting FBXW7-mediated SIRT1 ubiquitination. FBXW7/SIRT1 axis mediated the effect of TUG1 on OGD/R-induced neuronal apoptosis by regulating mitophagy. Introduction jewett accounting thunder bayWebLncRNA TUG1 promotes the ASMCs proliferation and migration, and reduces apoptosis In the ASMCs cells isolated from the asthma rats, we had found that TUG1 was increased. Thus, in order to discover the roles of TUG1 for the ASMCs, silencing and overexpression of TUG1 was constructed using the siRNA and plasmid transfection ( Figure 2A ). jewett acoustics llcWebThe lncRNA taurine-upregulated gene 1 (TUG1) directly binds to polycomb repressive complex 2 (PRC2) or PRC1 represses gene expression, and has been reported to participate in oncogenic processes. 11,12 TUG1 acts as a key regulator of drug resistance by sponging miRNAs and involved in the control of some cancer-related genes. 13–15 instal budotechWebLncRNA TUG1 Was Induced in the HDM-Stimulated Macrophages As shown in Figure 2A, LncRNA TUG1 was increased in the macrophages stimulated by HDM in a dose-dependent manner. Meanwhile, the level of miR-29c significantly decreased even at the low dose of HDM stimulation ( Figure 2B ). jewett and companyjewett agencies of grand rapidsWebFeb 22, 2024 · LncRNA TUG1, along with other lncRNAs, have been shown to regulate the cell cycle, which is specifically increased during aging [ 49 ]. LncRNA TUG1 has also been shown to disrupt the expression of the Homeobox (HOX) gene family, such as HOXB7, thereby leading to an aging phenotype [ 50 ]. jewett academy of the artsWebDec 6, 2016 · Among these, TUG1 (NR_002323.1) was the only lncRNA, which was also highly expressed as determined by RNA-seq analysis and possessed multiple RBPJκ motifs around its promoter region . jewett agency grand rapids mi